What is the primary anabolic hormone involved in muscle tissue growth and remodeling?

The primary anabolic hormone involved in muscle tissue growth and remodeling is insulin-like growth factors (IGFs). IGFs play a crucial role in cell growth and development, particularly in skeletal muscle. They stimulate the incorporation of amino acids into proteins, which is essential for muscle repair and hypertrophy following resistance training or injury.

IGFs are primarily produced in the liver as a response to growth hormone stimulation, but they have a direct effect on muscle tissues and contribute to muscle hypertrophy and regeneration. Elevated levels of IGF are associated with increased muscle protein synthesis, facilitating the growth of muscle fibers.

While other hormones such as testosterone and growth hormone also play significant roles in muscle growth, IGFs are specifically regarded as central mediators of the anabolic effects of these hormones at the cellular level, particularly after exercise. Therefore, they are crucial for the long-term adaptation of muscle tissue, which is essential for enhancing performance and strength.